Cystatin B/Stefin B Antibody (S02-7D7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19854

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19854-100ul
NBP3-19854-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-7D7

Concentration

0.3 mg/ml

View all Cystatin B Antibodies »

Product Summary for Cystatin B/Stefin B Antibody (S02-7D7)

Immunogen

A synthetic peptide of human Cystatin B/Stefin B (Uniprot # P04080)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

11 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cystatin B/Stefin B Antibody (S02-7D7)

Western Blot: Cystatin B/Stefin B Antibody (S02-7D7) [NBP3-19854]

Western Blot: Cystatin B/Stefin B Antibody (S02-7D7) [NBP3-19854]

Western Blot: Cystatin B/Stefin B Antibody (S02-7D7) [NBP3-19854] - Western blot detection of Cystatin B/Stefin B in Hela, A549, HL-60 using NBP3-19854 (1:1000 diluted)
Immunohistochemistry-Paraffin: Cystatin B/Stefin B Antibody (S02-7D7) [NBP3-19854]

Immunohistochemistry-Paraffin: Cystatin B/Stefin B Antibody (S02-7D7) [NBP3-19854]

Immunohistochemistry-Paraffin: Cystatin B/Stefin B Antibody (S02-7D7) [NBP3-19854] - Immunohistochemistry of Cystatin B/Stefin B in paraffin-embedded Human tonsil using NBP3-19854 at dilution 1/50

Applications for Cystatin B/Stefin B Antibody (S02-7D7)

Application
Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cystatin B

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Alternate Names

CSTB, Stefin B

Gene Symbol

CSTB

Additional Cystatin B Products

Product Documents for Cystatin B/Stefin B Antibody (S02-7D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cystatin B/Stefin B Antibody (S02-7D7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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