Cysteine Conjugate beta-Lyase/CCBL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83316

Novus Biologicals, part of Bio-Techne
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NBP1-83316
NBP1-83316-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cysteine Conjugate beta-Lyase/CCBL1 Antibodies »

Product Summary for Cysteine Conjugate beta-Lyase/CCBL1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cysteine Conjugate beta-Lyase/CCBL1 Antibody

Immunocytochemistry/ Immunofluorescence: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [NBP1-83316]

Immunocytochemistry/ Immunofluorescence: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [NBP1-83316]

Immunocytochemistry/Immunofluorescence: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [NBP1-83316] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
Immunohistochemistry-Paraffin: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [NBP1-83316]

Immunohistochemistry-Paraffin: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [NBP1-83316]

Immunohistochemistry-Paraffin: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [NBP1-83316] - Staining of human urinary bladder shows strong positivity in urothelial cells.

Applications for Cysteine Conjugate beta-Lyase/CCBL1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cysteine Conjugate beta-Lyase/CCBL1

CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

Alternate Names

CCBL1, Cysteine Conjugate betaLyase, Glutamine Transaminase K, KAT1, KATI, Kyneurenine Aminotransferase I

Gene Symbol

KYAT1

Additional Cysteine Conjugate beta-Lyase/CCBL1 Products

Product Documents for Cysteine Conjugate beta-Lyase/CCBL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cysteine Conjugate beta-Lyase/CCBL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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