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Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-02340

Novus Biologicals, part of Bio-Techne
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NBP1-02340

Key Product Details

Species Reactivity

Validated:

Human, Equine

Cited:

Human

Predicted:

Monkey (94%), Mouse (94%), Primate (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from 1st extracellular domain of human Cysteinyl Leukotriene R2/CysLTR2.

Epitope

1st extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%), Gorilla (94%), Panda (94%), Canine (88%), Bovine (88%), Hamster (88%), Elephant (88%), Rabbit (88%), Opossum (88%), Porcine (88%).

Specificity

Human Cysteinyl Leukotriene R2/CysLTR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR109B (59%), OXGR1 (59%), GPR81 (59%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free [NBP1-02340]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free [NBP1-02340]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free [NBP1-02340] - Staining of Human Heart tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Applications for Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Cysteinyl Leukotriene R2/CysLTR2

Cysteinyl leukotriene receptor 2 (CysLT2) is a Chemoattractant Receptor that binds neutrophil chemoattractants such as cysteinyl leukotrienes. These ligands have potent proinflammatory activity and are implicated in many features of asthma including edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Activation of cysteinyl leukotriene receptor 2 induces cell contraction and/or relaxation.

Long Name

Cysteinyl Leukotriene Receptor 2

Alternate Names

CysLT2, CysLTR2, Cysteinyl LeukotrieneR2, HG57, HPN321, KPG_011

Entrez Gene IDs

57105 (Human)

Gene Symbol

CYSLTR2

UniProt

Additional Cysteinyl Leukotriene R2/CysLTR2 Products

Product Documents for Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cysteinyl Leukotriene R2/CysLTR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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