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Cysteinyl Leukotriene R2/CysLTR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14292

Novus Biologicals, part of Bio-Techne
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NBP3-14292

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from C-Terminus cytoplasmic domain of human CYSLTR2.

Epitope

C-Terminus

Reactivity Notes

Expected reactivity based on percent sequence identity: Marmoset, Porcine (80%)

Specificity

Human Cysteinyl Leukotriene R2/CysLTR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Cysteinyl Leukotriene R2/CysLTR2 Antibody

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP3-14292]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP3-14292]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP3-14292] - Immunohistochemistry of formalin-fixed, paraffin-embedded human spleen after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP3-14292]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP3-14292]

Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NBP3-14292] - Immunohistochemistry of formalin-fixed, paraffin-embedded human heart after heat-induced antigen retrieval.

Applications for Cysteinyl Leukotriene R2/CysLTR2 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Cysteinyl Leukotriene R2/CysLTR2

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. CysLTR2 seems to play a major role in endocrine and cardiovascular systems. Stimulation of CysLTR2 by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium.

Long Name

Cysteinyl Leukotriene Receptor 2

Alternate Names

CysLT2, CysLTR2, Cysteinyl LeukotrieneR2, HG57, HPN321, KPG_011

Gene Symbol

CYSLTR2

Additional Cysteinyl Leukotriene R2/CysLTR2 Products

Product Documents for Cysteinyl Leukotriene R2/CysLTR2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cysteinyl Leukotriene R2/CysLTR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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