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Cytochrome P450 26B1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33476

Novus Biologicals, part of Bio-Techne
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NBP1-33476

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Zebrafish

Cited:

Human

Predicted:

Bovine (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Cytochrome P450 26B1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Xenopus tropicalis (81%).

Localization

Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein, Endoplasmic reticulum membrane, Microsome membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cytochrome P450 26B1 Antibody

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476]

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476]

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476] - Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with CYP26B1 antibody [N2C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476]

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476]

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476] - Various tissue extracts (50 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CYP26B1 antibody [N2C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476]

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476]

Western Blot: Cytochrome P450 26B1 Antibody [NBP1-33476] - Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with CYP26B1 antibody [N2C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for Cytochrome P450 26B1 Antibody

Application
Recommended Usage

Immunohistochemistry

Assay dependent

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 26B1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.

Alternate Names

CYP26A2, Cytochrome P450 26A2, cytochrome P450 26B1, cytochrome P450 CYP26B1 variant 2, Cytochrome P450 retinoic acid-inactivating 2, cytochrome P450 retinoid metabolizing protein, cytochrome P450, family 26, subfamily B, polypeptide 1, Cytochrome P450RAI-2, DKFZp686G0638, EC 1.14, MGC129613, P450RAI2, P450RAI-2, Retinoic acid-metabolizing cytochrome

Gene Symbol

CYP26B1

Additional Cytochrome P450 26B1 Products

Product Documents for Cytochrome P450 26B1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cytochrome P450 26B1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.