Cytochrome P450 2A6 Antibody (OTI1D2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-01437

Novus Biologicals, part of Bio-Techne
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NBP2-01437
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Conjugate
Catalog #
Alexa Fluor 350
NBP2-70524AF350
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Alexa Fluor 405
NBP2-70524AF405
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Alexa Fluor 488
NBP2-70524AF488
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Alexa Fluor 532
NBP2-70524AF532
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Alexa Fluor 594
NBP2-70524AF594
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Alexa Fluor 647
NBP2-70524AF647
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Alexa Fluor 700
NBP2-70524AF700
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Alexa Fluor 750
NBP2-70524AF750
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Allophycocyanin
NBP2-70524APC
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Allophycocyanin/Cy7
NBP2-70524APCCY7
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Biotin
NBP2-70524B
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CoraFluor 1
NBP2-70524CL1
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DyLight 350
NBP2-70524UV
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DyLight 405
NBP2-70524V
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DyLight 488
NBP2-70524G
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DyLight 550
NBP2-70524R
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DyLight 594
NBP2-70524DL594
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DyLight 650
NBP2-70524C
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DyLight 680
NBP2-70524FR
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DyLight 755
NBP2-70524IR
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FITC
NBP2-70524F
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HRP
NBP2-70524H
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Janelia Fluor 525
NBP2-70524JF525
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Janelia Fluor 549
NBP2-70524JF549
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Janelia Fluor 585
NBP2-70524JF585
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Janelia Fluor 635
NBP2-70524JF635
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Janelia Fluor 646
NBP2-70524JF646
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Janelia Fluor 669
NBP2-70524JF669
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mFluor Violet 450 SE
NBP2-70524MFV450
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mFluor Violet 500 SE
NBP2-70524MFV500
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mFluor Violet 610 SE
NBP2-70524MFV610
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PE
NBP2-70524PE
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PE/Atto594
NBP2-70524PEATT594
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PE/Cy5.5
NBP2-70524PECY55
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PE/Cy7
NBP2-70524PECY7
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PerCP
NBP2-70524PCP
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Monkey, Primate

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI1D2

Concentration

1.3 mg/ml

View all Cytochrome P450 2A6 Antibodies »

Product Summary for Cytochrome P450 2A6 Antibody (OTI1D2)

Immunogen

Full length human recombinant protein of human CYP2A6(NP_000753) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

56.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cytochrome P450 2A6 Antibody (OTI1D2)

Western Blot: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437]

Western Blot: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437]

Western Blot: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Analysis of extracts (35ug) from 9 different cell lines by using anti-Cytochrome P450 2A6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemistry-Paraffin: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437]

Immunohistochemistry-Paraffin: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437]

Immunohistochemistry-Paraffin: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Staining of paraffin-embedded Human prostate tissue using anti-Cytochrome P450 2A6 mouse monoclonal antibody.
Flow Cytometry: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437]

Flow Cytometry: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437]

Flow Cytometry: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Analysis of Jurkat cells, using anti-CYP2A6 antibody , (Red), compared to a nonspecific negative control antibody, (Blue).
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Applications for Cytochrome P450 2A6 Antibody (OTI1D2)

Application
Recommended Usage

Flow Cytometry

1:100

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:500-2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 2A6

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq].

Alternate Names

Coumarin 7-hydroxylase, CPA6, CYP2A3P450C2A, CYP2AEC 1.14.14.1, CYPIIA6, cytochrome P450 2A6, Cytochrome P450 IIA3, Cytochrome P450(I), cytochrome P450, family 2, subfamily A, polypeptide 6, cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6, flavoprotein-linked monooxygenase, P450PB, xenobiotic monooxygenase

Entrez Gene IDs

1548 (Human)

Gene Symbol

CYP2A6

Additional Cytochrome P450 2A6 Products

Product Documents for Cytochrome P450 2A6 Antibody (OTI1D2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytochrome P450 2A6 Antibody (OTI1D2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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