Cytochrome P450 3A5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00001577-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 3A5 Antibodies »

Product Specifications

Immunogen

CYP3A5 (AAH33862.1, 1 a.a. - 502 a.a.) full-length human protein. MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGTLSGE

Specificity

CYP3A5 - cytochrome P450, family 3, subfamily A, polypeptide 5,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Cytochrome P450 3A5 Antibody

Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P]

Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P]

Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P] - Analysis of CYP3A5 expression in human liver.
Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P]

Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P]

Western Blot: Cytochrome P450 3A5 Antibody [H00001577-B01P] - Analysis of CYP3A5 expression in transfected 293T cell line by CYP3A5 polyclonal antibody. Lane1:CYP3A5 transfected lysate(55.22 KDa). Lane2:Non-transfected lysate.

Applications for Cytochrome P450 3A5 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 3A5

This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. [provided by RefSeq]

Long Name

Cytochrome P450 3A5

Alternate Names

CYP3A5, CYPIIIA5

Entrez Gene IDs

1577 (Human)

Gene Symbol

CYP3A5

UniProt

AAH33862.1 (Human)

Additional Cytochrome P450 3A5 Products

Product Documents for Cytochrome P450 3A5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cytochrome P450 3A5 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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