Cytochrome P450 4F11 Antibody (F21 P6 F5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-66614

Novus Biologicals, part of Bio-Techne
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NBP2-66614
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # F21 P6 F5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cytochrome P450 4F11 Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human Cytochrome P450 4F11 protein (Uniprot: A8K059) and mouse myeloma Ag8563 cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Cytochrome P450 4F11 Antibody (F21 P6 F5)

Immunohistochemistry: Cytochrome P450 4F11 Antibody (F21 P6 F5) [NBP2-66614]

Immunohistochemistry: Cytochrome P450 4F11 Antibody (F21 P6 F5) [NBP2-66614]

Immunohistochemistry: Cytochrome P450 4F11 Antibody (F21 P6 F5) [NBP2-66614] - A. Immunohistochemical staining of human liposarcoma cells using CYP4F11 antibody (Cat. No. NBP2-66614).B. Western blot using CYP4F11 antibody one normal (2) and cancerous (3) kidney cell lysates.

Applications for Cytochrome P450 4F11 Antibody (F21 P6 F5)

Application
Recommended Usage

Immunohistochemistry

1-5 ug/ml

Immunohistochemistry-Paraffin

1-5 ug/ml

Western Blot

1-2 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cytochrome P450 4F11

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.

Alternate Names

CYPIVF11, cytochrome P450 4F11, cytochrome P450, family 4, subfamily F, polypeptide 11, cytochrome P450, subfamily IVF, polypeptide 11, EC 1.14.14.1

Gene Symbol

CYP4F11

UniProt

A8K059 (Human)

Additional Cytochrome P450 4F11 Products

Product Documents for Cytochrome P450 4F11 Antibody (F21 P6 F5)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cytochrome P450 4F11 Antibody (F21 P6 F5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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