Cytokeratin 75 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56047

Novus Biologicals, part of Bio-Techne
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NBP2-56047
NBP2-56047-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cytokeratin 75 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ('LYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGF',)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cytokeratin 75 Antibody

Immunocytochemistry/ Immunofluorescence: Cytokeratin 75 Antibody [NBP2-56047]

Immunocytochemistry/ Immunofluorescence: Cytokeratin 75 Antibody [NBP2-56047]

Immunocytochemistry/Immunofluorescence: Cytokeratin 75 Antibody [NBP2-56047] - Staining of human cell line PC-3 shows localization to plasma membrane & cytosol. Antibody staining is shown in green.

Applications for Cytokeratin 75 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cytokeratin 75

Keratin-75 is a protein that plays a central role in hair and nail formation, as it is an important component of the keratin intermediate filaments that are located in the companion layer of the hair follicle, and is 551 amino acids long with a weight of approximately 60 kDa. Studies are being conducted on diseases and disorders related to this protein including loose anagen hair syndrome, pseudofolliculitis barbae, histocytoma, Marek disease, dermatitis, alopecia, pharyngitis, lung cancer, breast cancer, esophagitis, hepatitis, and neuronitis. Keratin-75 has also been shown to have interactions with GABARAP, GABARAPL1, MAP1LC3A, MAR1LC3B, and AMBRA1.

Alternate Names

CK-75, cytokeratin-75, hK6hf, K6HFcytokeratin type II, K75, KB18, keratin 75, keratin, type II cytoskeletal 75, Keratin-6 hair follicle, Keratin-75, PFB, type II keratin-18, Type II keratin-K6hf, Type-II keratin Kb18

Gene Symbol

KRT75

Additional Cytokeratin 75 Products

Product Documents for Cytokeratin 75 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cytokeratin 75 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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