DAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87245

Novus Biologicals, part of Bio-Techne
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NBP2-87245
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all DAP1 Antibodies »

Product Summary for DAP1 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of DAP1. Peptide sequence: PSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHPSPRTQHIQQ The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for DAP1 Antibody

Western Blot: DAP1 Antibody [NBP2-87245]

Western Blot: DAP1 Antibody [NBP2-87245]

Western Blot: DAP1 Antibody [NBP2-87245] - WB Suggested Anti-DAP Antibody. Titration: 1.0 ug/ml. Positive Control: HCT15 Whole Cell
Immunohistochemistry-Paraffin: DAP1 Antibody [NBP2-87245]

Immunohistochemistry-Paraffin: DAP1 Antibody [NBP2-87245]

Immunohistochemistry-Paraffin: DAP1 Antibody [NBP2-87245] - Rabbit Anti-DAP Antibody. Formalin Fixed Paraffin Embedded Tissue: Human Heart Tissue. Observed Staining: Cytoplasm in cardiomyocytes and endothelial cells in capillaries. Primary Antibody Concentration: 1:100.

Applications for DAP1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DAP1

Death associated protein 1 (DAP-1) is a 15-kDa protein that functions as a positive mediator of cell death initiated by interferon (IFN-) gamma (1,2). DAP-1 is proline rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites (1). It is localized to the cytoplasm, but the detailed mechanism of its pro-apoptotic function is unclear. DAP-1 and DAP kinase, a unique, 160-kDa calmodulin-dependent serine/threonine kinase, are both unique candidates for positive mediators of programmed cell death induced by IFN-gamma (3).

Alternate Names

DAP1, DAP-1, death-associated protein, death-associated protein 1, MGC99796

Gene Symbol

DAP

Additional DAP1 Products

Product Documents for DAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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