DAZ1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46743

Novus Biologicals, part of Bio-Techne
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NBP2-46743
NBP2-46743-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DAZ1 Antibodies »

Product Summary for DAZ1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NDVDVQKIVGSQIHFHGKKLKLGPAIRKQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DAZ1 Antibody

Immunohistochemistry: DAZ1 Antibody [NBP2-46743]

Immunohistochemistry: DAZ1 Antibody [NBP2-46743]

Immunohistochemistry: DAZ1 Antibody [NBP2-46743] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

Applications for DAZ1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DAZ1

DAZ1 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains.

Alternate Names

deleted in azoospermia, deleted in azoospermia 1, FLJ17175, SPGYDAZdeleted in azoospermia protein 1

Entrez Gene IDs

57055 (Human)

Gene Symbol

DAZ1

UniProt

Q86SG3 (Human)

Additional DAZ1 Products

Product Documents for DAZ1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DAZ1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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