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DCAMKL2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77128

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human DCLK2. The immunogen is located within the last 50 amino acids of DCLK2. Amino Acid Squence: PGGERAGTWRRHRD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

85 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DCAMKL2 Antibody - BSA Free

Western Blot: DCAMKL2 AntibodyBSA Free [NBP1-77128]

Western Blot: DCAMKL2 AntibodyBSA Free [NBP1-77128]

Western Blot: DCAMKL2 Antibody [NBP1-77128] - Analysis of DCLK2 in rat brain tissue lysate with DCLK2 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: DCAMKL2 Antibody - BSA Free [NBP1-77128]

Immunohistochemistry-Paraffin: DCAMKL2 Antibody - BSA Free [NBP1-77128]

Immunohistochemistry-Paraffin: DCAMKL2 Antibody [NBP1-77128] - Rat brain tissue with DCAMKL2 antibody at 5 ug/mL.
DCAMKL2 Antibody - BSA Free

Immunohistochemistry: DCAMKL2 Antibody - BSA Free [NBP1-77128] -

Immunohistochemistry: DCAMKL2 Antibody - BSA Free [NBP1-77128] - Immunohistochemistry of DLCK2 in rat brain tissue with DLCK2 antibody at 5 u/mL.

Applications for DCAMKL2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DCAMKL2

DCLK2 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK2 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK1 and DCLK2 transcripts are present in human fetal brain and the developing mouse embryo, suggesting that DCLK1 and DCLK2 may play roles in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization. Unlike DCLK1, DCLK2 expression does not change in DCX-null mice.

Alternate Names

CL2EC 2.7.11.1, CLICK-II, CLIK2, DCDC3, DCDC3BCaMK-like CREB regulatory kinase 2, DCK2DCAMKL2, DKFZp761I032, doublecortin and CaM kinase-like 2, Doublecortin domain-containing protein 3B, Doublecortin-like and CAM kinase-like 2, doublecortin-like kinase 2CLICK2, EC 2.7.11, MGC45428, serine/threonine-protein kinase DCLK2

Gene Symbol

DCLK2

Additional DCAMKL2 Products

Product Documents for DCAMKL2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DCAMKL2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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