DCLK3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77129

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DCLK3 Antibodies »

Product Summary for DCLK3 Antibody - BSA Free

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human DCLK3. The immunogen is located within the last 50 amino acids of DCLK3. Amino Acid Squence: SEGHFRSQHKRVVE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DCLK3 Antibody - BSA Free

Western Blot: DCLK3 AntibodyBSA Free [NBP1-77129]

Western Blot: DCLK3 AntibodyBSA Free [NBP1-77129]

Western Blot: DCLK3 Antibody [NBP1-77129] - K562 cell lysate at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: DCLK3 Antibody - BSA Free [NBP1-77129]

Immunocytochemistry/ Immunofluorescence: DCLK3 Antibody - BSA Free [NBP1-77129]

Immunocytochemistry/Immunofluorescence: DCLK3 Antibody [NBP1-77129] - Staining of DCLK3 in mouse brain tissue with at 20 ug/mL.
Immunohistochemistry-Paraffin: DCLK3 Antibody - BSA Free [NBP1-77129]

Immunohistochemistry-Paraffin: DCLK3 Antibody - BSA Free [NBP1-77129]

Immunohistochemistry-Paraffin: DCLK3 Antibody [NBP1-77129] - Staining of DCLK3 in mouse brain tissue with at 5 ug/mL.
View 1 more images

Applications for DCLK3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DCLK3

DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.

Alternate Names

CLICK-I, DCAMKL3, DCDC3CCLR, doublecortin and CaM kinase-like 3, Doublecortin domain-containing protein 3C, Doublecortin-like and CAM kinase-like 3, doublecortin-like kinase 3EC 2.7.11.1, EC 2.7.11, II-related, KIAA1765DCK3, serine/threonine-protein kinase DCLK3

Gene Symbol

DCLK3

UniProt

NP_208382 (Human)

Additional DCLK3 Products

Product Documents for DCLK3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DCLK3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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