DDR2 Antibody (3B11E4) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28883

Novus Biologicals, part of Bio-Techne
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NBP1-28883
NBP1-28883-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 3B11E4

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all DDR2 Antibodies »

Product Summary for DDR2 Antibody (3B11E4) - BSA Free

Immunogen

Purified recombinant fragment of human DDR2 expressed in E. Coli.

Specificity

Specific for DDR2.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for DDR2 Antibody (3B11E4) - BSA Free

Western Blot: DDR2 Antibody (3B11E4)BSA Free [NBP1-28883]

Western Blot: DDR2 Antibody (3B11E4)BSA Free [NBP1-28883]

Western Blot: DDR2 Antibody (3B11E4) [NBP1-28883] - Analysis using DDR2 mouse mAb against truncated DDR2 recombinant protein.
Immunocytochemistry/ Immunofluorescence: DDR2 Antibody (3B11E4) - BSA Free [NBP1-28883]

Immunocytochemistry/ Immunofluorescence: DDR2 Antibody (3B11E4) - BSA Free [NBP1-28883]

Immunocytochemistry/Immunofluorescence: DDR2 Antibody (3B11E4) [NBP1-28883] - Analysis of A549 cells using DDR2 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Immunohistochemistry-Paraffin: DDR2 Antibody (3B11E4) - BSA Free [NBP1-28883]

Immunohistochemistry-Paraffin: DDR2 Antibody (3B11E4) - BSA Free [NBP1-28883]

Immunohistochemistry-Paraffin: DDR2 Antibody (3B11E4) [NBP1-28883] - Analysis of human skeletal musle tissues using DDR2 mouse mAb.

Applications for DDR2 Antibody (3B11E4) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:200 - 1:1000

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DDR2

DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/ threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

Long Name

Discoidin Domain Receptor 2

Alternate Names

TKT, Trk3, Tyro-10

Entrez Gene IDs

4921 (Human)

Gene Symbol

DDR2

UniProt

Q16832

Additional DDR2 Products

Product Documents for DDR2 Antibody (3B11E4) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DDR2 Antibody (3B11E4) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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