DDR2 Antibody (HL1107)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13724

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-13724
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL1107

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DDR2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human DDR2. The exact sequence is proprietary.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

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Scientific Data Images for DDR2 Antibody (HL1107)

Western Blot: DDR2 Antibody (HL1107) [NBP3-13724]

Western Blot: DDR2 Antibody (HL1107) [NBP3-13724]

Western Blot: DDR2 Antibody (HL1107) [NBP3-13724] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with DDR2 antibody [HL1107] (NBP3-13724) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: DDR2 Antibody (HL1107) [NBP3-13724]

Immunohistochemistry-Paraffin: DDR2 Antibody (HL1107) [NBP3-13724]

Immunohistochemistry-Paraffin: DDR2 Antibody (HL1107) [NBP3-13724] - DDR2 antibody [HL1107] detects DDR2 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse heart. DDR2 stained by DDR2 antibody [HL1107] (NBP3-13724) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Western Blot: DDR2 Antibody (HL1107) [NBP3-13724]

Western Blot: DDR2 Antibody (HL1107) [NBP3-13724]

Western Blot: DDR2 Antibody (HL1107) [NBP3-13724] - U87-MG whole cell and membrane extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with DDR2 antibody [HL1107] (NBP3-13724) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
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Applications for DDR2 Antibody (HL1107)

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DDR2

DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/ threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

Long Name

Discoidin Domain Receptor 2

Alternate Names

TKT, Trk3, Tyro-10

Gene Symbol

DDR2

Additional DDR2 Products

Product Documents for DDR2 Antibody (HL1107)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DDR2 Antibody (HL1107)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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