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DEC-205/CD205 Antibody (HD30) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-41003

Novus Biologicals, part of Bio-Techne
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NBP1-41003-0.1mg

Key Product Details

Species Reactivity

Human, Primate

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # HD30

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Purified extracellular domain of human CD205-IgG1 Fc fusion protein.

Specificity

This antibody specifically recognises CD205, otherwise known as DEC205, a type I transmembrane glycoprotein and member of the macrophage mannose receptor family of C-type lectins, predominantly expressed by human dendritic cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for DEC-205/CD205 Antibody (HD30) - BSA Free

Flow Cytometry: DEC-205/CD205 Antibody (HD30) - BSA Free [NBP1-41003]

Flow Cytometry: DEC-205/CD205 Antibody (HD30) - BSA Free [NBP1-41003]

Flow Cytometry: Renal Cell Carcinoma (gp200) Antibody (HD30) [NBP1-41003] - KM-H2 cells.
Flow Cytometry: DEC-205/CD205 Antibody (HD30) - BSA Free [NBP1-41003]

Flow Cytometry: DEC-205/CD205 Antibody (HD30) - BSA Free [NBP1-41003]

Flow Cytometry: Renal Cell Carcinoma (gp200) Antibody (HD30) [NBP1-41003] - KM-H2 cells stained with Mouse anti Human CD205

Applications for DEC-205/CD205 Antibody (HD30) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:200

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
DEC-205/CD205 Antibody (HD30) has been validated for IHC-Fr, but not for IHC-P.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DEC-205/CD205

gp200 is a surface membrane glycoprotein expressed on human embryonal carcinoma and is a malignant stem cell of testicular tumors. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Of other normal tissues examined, the gp200 is also localized along the luminal surfaces of breast lobules and ducts, the luminal surface of the epididymal tubular epithelium, within the cytoplasm of parathyroid parenchymal cells, and focally within the colloid of thyroid follicles. Thirty one other normal tissues do not express similar or cross reacting antigens. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas.

Alternate Names

CD205, DEC205, Ly75

Entrez Gene IDs

4065 (Human)

Gene Symbol

LY75

UniProt

Additional DEC-205/CD205 Products

Product Documents for DEC-205/CD205 Antibody (HD30) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DEC-205/CD205 Antibody (HD30) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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