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DEDD Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76527

Novus Biologicals, part of Bio-Techne
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NBP2-76527

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for DEDD Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RGRATLGSQRKRRKSVTPDPKEKQTCDIRLRVRAEYCQHETALQGNVFSNKQDPLERQFERFNQANTILKSRDLGSIICDIKFSELTYLDAFWRDYINGSLLEALKGVFITDSLKQAVGHEAIKLLVNV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DEDD Antibody

Western Blot: DEDD Antibody [NBP2-76527]

Western Blot: DEDD Antibody [NBP2-76527]

Western Blot: DEDD Antibody [NBP2-76527] - Analysis in human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: DEDD Antibody [NBP2-76527]

Immunocytochemistry/ Immunofluorescence: DEDD Antibody [NBP2-76527]

Immunocytochemistry/Immunofluorescence: DEDD Antibody [NBP2-76527] - Staining of human cell line MCF7 shows localization to nucleoplasm. Antibody staining is shown in green.

Applications for DEDD Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DEDD

DEDD, also known as Death effector domain-containing protein, consists of a 36.8 kDa and a 40.4 kDa isoform and is involved in regulating the degradation of CASP3 in certain substances during apoptosis. Current research is exploring the effect of the protein on diseases such as dental fluorosis and dental caries. The protein is involved in transcription pathways with APLP2, CASP8, DEDD2, SMAD3, and CASP10.

Alternate Names

CASP8IP1, death effector domain containing, death effector domain-containing, death effector domain-containing protein, Death effector domain-containing testicular molecule, DEDD1, DEDPro1, DEFTKE05, FLDED1, FLDED-1

Gene Symbol

DEDD

Additional DEDD Products

Product Documents for DEDD Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DEDD Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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