Defensin alpha 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13910

Novus Biologicals, part of Bio-Techne
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NBP2-13910
NBP2-13910-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Defensin alpha 4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SSALQVSGSTRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Defensin alpha 4 Antibody

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910]

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910]

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910] - Staining of human lymph node shows positivity in lymphoid cells.
Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910]

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910]

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910] - Staining of human bone marrow shows positivity in hematopoietic cells.
Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910]

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910]

Immunohistochemistry-Paraffin: Defensin alpha 4 Antibody [NBP2-13910] - Staining of human cerebral cortex shows no positivity as expected.
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Applications for Defensin alpha 4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Defensin alpha 4

Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel.

Alternate Names

corticostatin, DEF4, defensin, alpha 4, corticostatin, defensin, alpha 4, preproprotein, HNP-4, HP4, HP-4, MGC120099, MGC138296, neutrophil defensin 4

Gene Symbol

DEFA4

Additional Defensin alpha 4 Products

Product Documents for Defensin alpha 4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Defensin alpha 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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