Derlin-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47485

Novus Biologicals, part of Bio-Techne
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NBP2-47485
NBP2-47485-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Derlin-2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NYNPLPEERPGGFAWGEGQRLGG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Derlin-2 Antibody

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485] - Staining in human thyroid gland and skeletal muscle tissues using anti-DERL2 antibody. Corresponding DERL2 RNA-seq data are presented for the same tissues.
Western Blot: Derlin-2 Antibody [NBP2-47485]

Western Blot: Derlin-2 Antibody [NBP2-47485]

Western Blot: Derlin-2 Antibody [NBP2-47485] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line U-251 MG.
Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485] - Staining of human skeletal muscle shows low expression as expected.
View 1 more images

Applications for Derlin-2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Derlin-2

DERL2 (Derlin 2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Alternate Names

carcinoma related, Degradation in endoplasmic reticulum protein 2, Der1-like domain family, member 2, Der1-like protein 2, DER2, derlin-2, F-LAN-1DERtrin-2, FLANa, F-LANaCGI-101

Gene Symbol

DERL2

Additional Derlin-2 Products

Product Documents for Derlin-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Derlin-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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