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Derlin-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98598

Novus Biologicals, part of Bio-Techne
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NBP2-98598-100ul
NBP2-98598-50ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human Derlin-2 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Derlin-2 Antibody

Immunocytochemistry/ Immunofluorescence: Derlin-2 Antibody [NBP2-98598]

Immunocytochemistry/ Immunofluorescence: Derlin-2 Antibody [NBP2-98598]

Immunocytochemistry/Immunofluorescence: Derlin-2 Antibody [NBP2-98598] - Immunofluorescence staining of Derlin-2 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human Derlin-2 polyclonal antibody (dilution ratio 1:200) at 4C overnight. Then cells were stained with the Alexa Fluor(R)488-conjugated Goat Anti-rabbit IgG Secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.
Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-98598]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-98598]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-98598] - Immunochemical staining of human Derlin-2 in human thyroid carcinoma with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-98598]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-98598]

Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-98598] - Immunochemical staining of human Derlin-2 in human lymph node with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.

Applications for Derlin-2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:500

Immunohistochemistry-Paraffin

1:200-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Derlin-2

DERL2 (Derlin 2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Alternate Names

carcinoma related, Degradation in endoplasmic reticulum protein 2, Der1-like domain family, member 2, Der1-like protein 2, DER2, derlin-2, F-LAN-1DERtrin-2, FLANa, F-LANaCGI-101

Gene Symbol

DERL2

Additional Derlin-2 Products

Product Documents for Derlin-2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Derlin-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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