Desert Hedgehog/Dhh Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00050846-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Desert Hedgehog/Dhh Antibodies »

Product Specifications

Immunogen

DHH (NP_066382.1, 1 a.a. - 396 a.a.) full-length human protein. MALLTNLLPLCCLALLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPVLLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSVLAPGGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPGGAVQPTGMHWYSRLLYRLAEELLG

Specificity

DHH - desert hedgehog homolog (Drosophila),

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for Desert Hedgehog/Dhh Antibody

Western Blot: Desert Hedgehog/Dhh Antibody [H00050846-B01P]

Western Blot: Desert Hedgehog/Dhh Antibody [H00050846-B01P]

Western Blot: Desert Hedgehog/Dhh Antibody [H00050846-B01P] - Analysis of DHH expression in transfected 293T cell line by DHH polyclonal antibody. Lane 1: DHH transfected lysate(43.56 KDa). Lane 2: Non-transfected lysate.

Applications for Desert Hedgehog/Dhh Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Use in Immunohistochemistry-paraffin reported in scientific literature (PMID: 28881358).

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Desert Hedgehog/Dhh

This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq]

Alternate Names

DHH

Entrez Gene IDs

50846 (Human)

Gene Symbol

DHH

UniProt

NP_066382.1 (Human)

Additional Desert Hedgehog/Dhh Products

Product Documents for Desert Hedgehog/Dhh Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Desert Hedgehog/Dhh Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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