Desert Hedgehog/Dhh Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-42834

Novus Biologicals, part of Bio-Techne
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NBP2-42834
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Desert Hedgehog/Dhh Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Desert Hedgehog/Dhh. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Desert Hedgehog/Dhh Antibody

Western Blot: Desert Hedgehog/Dhh Antibody [NBP2-42834]

Western Blot: Desert Hedgehog/Dhh Antibody [NBP2-42834]

Western Blot: Desert Hedgehog/Dhh Antibody [NBP2-42834] - Analysis of 30 ug whole cell lysate. A: A431 10% SDS PAGE diluted at 1:10000.

Applications for Desert Hedgehog/Dhh Antibody

Application
Recommended Usage

Western Blot

1:5000-1:20000
Application Notes
IHC-FR-Assay dependent

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Desert Hedgehog/Dhh

Dhh encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq]

Alternate Names

DHH

Gene Symbol

DHH

Additional Desert Hedgehog/Dhh Products

Product Documents for Desert Hedgehog/Dhh Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Desert Hedgehog/Dhh Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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