Desmocollin-3 Antibody (4D2)

Novus Biologicals, part of Bio-Techne | Catalog # H00001825-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 4D2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Desmocollin-3 Antibodies »

Product Specifications

Immunogen

DSC3 (NP_001932, 585 a.a. ~ 684 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. CKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRST

Specificity

DSC3 - desmocollin 3

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Desmocollin-3 Antibody (4D2)

Western Blot: Desmocollin-3 Antibody (4D2) [H00001825-M01]

Western Blot: Desmocollin-3 Antibody (4D2) [H00001825-M01]

Western Blot: Desmocollin-3 Antibody (4D2) [H00001825-M01] - DSC3 monoclonal antibody (M01), clone 4D2 Western Blot analysis of DSC3 expression in A-431 ( Cat # L015V1 ).
Immunocytochemistry/ Immunofluorescence: Desmocollin-3 Antibody (4D2) [H00001825-M01]

Immunocytochemistry/ Immunofluorescence: Desmocollin-3 Antibody (4D2) [H00001825-M01]

Immunocytochemistry/Immunofluorescence: Desmocollin-3 Antibody (4D2) [H00001825-M01] - Analysis of monoclonal antibody to DSC3 on A-431 cell. Antibody concentration 10 ug/ml.
Sandwich ELISA: Desmocollin-3 Antibody (4D2) [H00001825-M01] - Detection limit for recombinant GST tagged DSC3 is approximately 1ng/ml as a capture antibody.

Applications for Desmocollin-3 Antibody (4D2)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Desmocollin-3

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Alternate Names

CDHF3, Desmocollin3, DSC3, DSC4, HT-CP

Entrez Gene IDs

1825 (Human)

Gene Symbol

DSC3

OMIM

600271 (Human)

UniProt

NP_001932 (Human)

Additional Desmocollin-3 Products

Product Documents for Desmocollin-3 Antibody (4D2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Desmocollin-3 Antibody (4D2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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