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Desmoglein-2 Antibody (8O0R6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16421

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-16421-100ul
NBP3-16421-20ul

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8O0R6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1001-1118 of human Desmoglein-2 (Q14126). PLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAGVPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Desmoglein-2 Antibody (8O0R6)

Western Blot: Desmoglein-2 Antibody (8O0R6) [NBP3-16421]

Western Blot: Desmoglein-2 Antibody (8O0R6) [NBP3-16421]

Western Blot: Desmoglein-2 Antibody (8O0R6) [NBP3-16421] - Western blot analysis of extracts of various cell lines, using Desmoglein-2 antibody (NBP3-16421) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Applications for Desmoglein-2 Antibody (8O0R6)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Desmoglein-2

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Alternate Names

CDHF5, Desmoglein2, DSG2, HDGC

Gene Symbol

DSG2

Additional Desmoglein-2 Products

Product Documents for Desmoglein-2 Antibody (8O0R6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Desmoglein-2 Antibody (8O0R6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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