Desmoglein-3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-54744

Novus Biologicals, part of Bio-Techne
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NBP2-54744
NBP2-54744-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Desmoglein-3 Antibodies »

Product Summary for Desmoglein-3 Antibody

Immunogen

This antibody was developed against a Recombinant Protein corresponding to amino acids: FRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFND

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Desmoglein-3 Antibody

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human testis.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human esophagus shows high expression.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744]

Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54744] - Staining of human stomach shows low expression as expected.
View 4 more images

Applications for Desmoglein-3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Desmoglein-3

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Alternate Names

CDHF6, Desmoglein3, DSG3

Gene Symbol

DSG3

Additional Desmoglein-3 Products

Product Documents for Desmoglein-3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Desmoglein-3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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