Desmoglein-4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31770

Novus Biologicals, part of Bio-Techne
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NBP2-31770
NBP2-31770-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Desmoglein-4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: DLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Desmoglein-4 Antibody

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770]

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770]

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770] - Staining of human skin show strong membranous positivity in hair follicle.
Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770]

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770]

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770]

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770]

Immunohistochemistry-Paraffin: Desmoglein-4 Antibody [NBP2-31770] - Staining of human duodenum shows no positivity in glandular cells as expected.
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Applications for Desmoglein-4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Desmoglein-4

DSG4, also known as Desmoglein-4, consists of a 113.8 kDa and a 115.5 kDa isoform and is located in the membrane of desmosomes where it moderates cell to cell adhesion. Diseases and disorders such as impetigo, pemphigus foliaceus, skin disease, prostatitis, hypotrichosis, and monilethrix have been researched with this protein. The protein interacts with other proteins including RAB24, MLST8, and PKP3.

Alternate Names

Cad13, CDGF13, CDHF13, Desmoglein4, DSG4

Gene Symbol

DSG4

UniProt

Q86SJ6 (Human)

Additional Desmoglein-4 Products

Product Documents for Desmoglein-4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Desmoglein-4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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