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DGKH Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85228

Novus Biologicals, part of Bio-Techne
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NBP1-85228
NBP1-85228-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for DGKH Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NKANPRCPESLTRDTATEIAINVKALYNETESLLVGRVPLQLESPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDEEPPMDCTKRNNRS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DGKH Antibody

Immunohistochemistry-Paraffin: DGKH Antibody [NBP1-85228]

Immunohistochemistry-Paraffin: DGKH Antibody [NBP1-85228]

Immunohistochemistry-Paraffin: DGKH Antibody [NBP1-85228] - Staining of human kidney shows strong cytoplasmic positivity in tubule cells.

Applications for DGKH Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DGKH

DGKH, also known as Diacylglycerol kinase eta, consists of four isoforms of sizes 134.9 kDa, 128 kDa, 122.4 kDa, and 120.6 kDa and is involved in activating the signaling pathway Ras/B-Raf/C-Raf/MEK/ERK in order to promote cell growth. Current research is exploring the effect of the protein on diseases and disorders such as measles, neuronitis, bipolar disorder, and schizophrenia. The protein interacts with AGPAT2, AGPAT4, CHPT1, ARRB1, and DGKD proteins while in hemostasis, signal transduction, and metabolic pathways.

Alternate Names

DAG kinase eta, DGKeta, DGK-eta, diacylglycerol kinase eta, diacylglycerol kinase, eta, Diglyceride kinase eta, DKFZp761I1510, EC 2.7.1.107

Gene Symbol

DGKH

Additional DGKH Products

Product Documents for DGKH Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DGKH Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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