DHRS4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83790

Novus Biologicals, part of Bio-Techne
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NBP1-83790
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DHRS4 Antibodies »

Product Summary for DHRS4 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DHRS4 Antibody

Western Blot: DHRS4 Antibody [NBP1-83790]

Western Blot: DHRS4 Antibody [NBP1-83790]

Western Blot: DHRS4 Antibody [NBP1-83790] - Analysis in human cell line MCF-7 and human cell line CACO-2.
Immunohistochemistry-Paraffin: DHRS4 Antibody [NBP1-83790]

Immunohistochemistry-Paraffin: DHRS4 Antibody [NBP1-83790]

Immunohistochemistry-Paraffin: DHRS4 Antibody [NBP1-83790] - Staining of human kidney shows strong cytoplasmic positivity in tubule cells.

Applications for DHRS4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For Fixation/Permeabilization: PFA/Triton X-100 is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DHRS4

Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones

Alternate Names

CR, dehydrogenase/reductase (SDR family) member 4, dehydrogenase/reductase (SDR family) member 4 like 2A, dehydrogenase/reductase SDR family member 4, EC 1.1.1, EC 1.1.1.184, FLJ11008, humNRDR, NADP-dependent retinol dehydrogenase, NRDRNADPH-dependent retinol dehydrogenase/reductase, Peroxisomal short-chain alcohol dehydrogenase, PHCR, PSCD, SCAD-SRLNADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, SDR25C1, SDR25C2, SDR-SRL, short chain dehydrogenase/reductase family 25C, member 1, short chain dehydrogenase/reductase family 25C, member 2, Short-chain dehydrogenase/reductase family member 4

Gene Symbol

DHRS4

Additional DHRS4 Products

Product Documents for DHRS4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DHRS4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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