DIAPH1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85246

Novus Biologicals, part of Bio-Techne
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NBP1-85246
NBP1-85246-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DIAPH1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAE

Reactivity Notes

Reactivity reported in scientific literature (PMID: 21886777).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DIAPH1 Antibody

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246]

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246]

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246]

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246]

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246]

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246]

Immunohistochemistry-Paraffin: DIAPH1 Antibody [NBP1-85246] - Staining of human lung shows strong cytoplasmic positivity in macrophages.
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Applications for DIAPH1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DIAPH1

Diaphanous 1 is a member of the Formin homology (FH) family of cytoskeletal organizer proteins. It is required for cytokinesis and transcriptional activation of the serum response factor. It has also been suggested to contribute to localized actin polymerization and stress fiber formation, both by recruiting profiling to sites of Rho action and by cooperating with ROCK. The human Diaphanous 1 gene is associated with Premature Ovarian Failure (POF) and Nonsyndromic Deafness (DFNA1), an autosomal dominant, fully penetrant progressive hearing loss.

Alternate Names

DIA1, diaphanous homolog 1 (Drosophila), hDIA1, homolog) 1, LFHL1FLJ25265

Gene Symbol

DIAPH1

Additional DIAPH1 Products

Product Documents for DIAPH1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DIAPH1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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