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DIS3 Antibody (2C7)

Novus Biologicals, part of Bio-Techne | Catalog # H00022894-M01

Novus Biologicals, part of Bio-Techne
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H00022894-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2C7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

KIAA1008 (NP_055768, 861 a.a. ~ 956 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKL

Specificity

KIAA1008 - KIAA1008 (2C7)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for DIS3 Antibody (2C7)

Immunocytochemistry/ Immunofluorescence: DIS3 Antibody (2C7) [H00022894-M01]

Immunocytochemistry/ Immunofluorescence: DIS3 Antibody (2C7) [H00022894-M01]

Immunocytochemistry/Immunofluorescence: DIS3 Antibody (2C7) [H00022894-M01] - Analysis of monoclonal antibody to DIS3 on HeLa cell . Antibody concentration 10 ug/ml.
Sandwich ELISA: DIS3 Antibody (2C7) [H00022894-M01] - Detection limit for recombinant GST tagged DIS3 is 0.1 ng/ml as a capture antibody.

Applications for DIS3 Antibody (2C7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DIS3

DIS3 is a component of the exosome 3'->5' exoribonuclease complex. Required for the 3'-processing of the 7S pre-RNA to the mature nuclear complex. Also associated with the GTPase Ran. Has a 3'-5' exonuclease activity

Alternate Names

2810028N01Rik, DIS3 mitotic control homolog (S. cerevisiae), dis3p, DKFZp667L1817, EC 3.1.13, EC 3.1.13.-, EC 3.1.26.-, EXOSC11, exosome complex exonuclease RRP44, exosome component 11, FLJ10484, KIAA1008RP11-342J4.3, MGC33035, mitotic control protein dis3 homolog, Protein DIS3 homolog, Ribosomal RNA-processing protein 44, RRP44bA555G22.1

Entrez Gene IDs

22894 (Human)

Gene Symbol

DIS3

Additional DIS3 Products

Product Documents for DIS3 Antibody (2C7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DIS3 Antibody (2C7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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