Dishevelled-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17787

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Dishevelled-1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dishevelled-1 Antibody

Western Blot: Dishevelled-1 Antibody [NBP3-17787]

Western Blot: Dishevelled-1 Antibody [NBP3-17787]

Western Blot: Dishevelled-1 Antibody [NBP3-17787] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10; Lane 2: RT4; Lane 3: U-251 MG; Lane 4: Human Plasma; Lane 5: Liver; Lane 6: Tonsil
Immunohistochemistry-Paraffin: Dishevelled-1 Antibody [NBP3-17787]

Immunohistochemistry-Paraffin: Dishevelled-1 Antibody [NBP3-17787]

Immunohistochemistry-Paraffin: Dishevelled-1 Antibody [NBP3-17787] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Applications for Dishevelled-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dishevelled-1

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq]

Alternate Names

Dishevelled1, Dsh, DVL1

Gene Symbol

DVL1

Additional Dishevelled-1 Products

Product Documents for Dishevelled-1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Dishevelled-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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