DLC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88824

Novus Biologicals, part of Bio-Techne
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NBP1-88824
NBP1-88824-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DLC1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVSLPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLCLTDDKQVLNTQGQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DLC1 Antibody

Western Blot: DLC1 Antibody [NBP1-88824]

Western Blot: DLC1 Antibody [NBP1-88824]

Western Blot: DLC1 Antibody [NBP1-88824] - Analysis in human cell line U-2197.
Immunocytochemistry/ Immunofluorescence: DLC1 Antibody [NBP1-88824]

Immunocytochemistry/ Immunofluorescence: DLC1 Antibody [NBP1-88824]

Immunocytochemistry/Immunofluorescence: DLC1 Antibody [NBP1-88824] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.
Immunohistochemistry-Paraffin: DLC1 Antibody [NBP1-88824]

Immunohistochemistry-Paraffin: DLC1 Antibody [NBP1-88824]

Immunohistochemistry-Paraffin: DLC1 Antibody [NBP1-88824] - Staining of human duodenum shows distinct positivity of microvilli in glandular cells.

Applications for DLC1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500-1:5000

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DLC1

DLC1 is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. Alternative splicing at this locus results in several transcript variants encoding different isoforms.

Alternate Names

ARHGAP7 STARD12 deleted in liver cancer 1 variant 2, deleted in liver cancer 1, Deleted in liver cancer 1 protein, DLC-1, FLJ21120, HP, HP protein, KIAA1723, p122-RhoGAP, rho GTPase-activating protein 7, Rho-GTPase-activating protein 7, Rho-type GTPase-activating protein 7, StARD12, StAR-related lipid transfer (START) domain containing 12, StAR-related lipid transfer protein 12, START domain-containing protein 12

Gene Symbol

DLC1

Additional DLC1 Products

Product Documents for DLC1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DLC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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