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DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28605

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # BIIB059

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

CLEC4C

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.62 kDa.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized

DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized

ELISA: DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized[NBP3-28605] -

Immobilized Ma CLEC4C His at 2 ug/mL can bind DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized, EC50=0.04315 ug/mL.

Applications for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: DLEC/CLEC4C/BDCA-2

Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

Long Name

Dendritic Cell Lectin

Alternate Names

BDCA-2, BDCA2, CD303, CLEC4C, CLECSF11, CLECSF7

Gene Symbol

CLEC4C

UniProt

Additional DLEC/CLEC4C/BDCA-2 Products

Product Documents for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DLEC/CLEC4C/BDCA-2 Antibody (BIIB059) - Humanized

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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