DLST Antibody (4D7)

Novus Biologicals, part of Bio-Techne | Catalog # H00001743-M01-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 4D7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DLST Antibodies »

Product Specifications

Immunogen

DLST (NP_001924, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAE

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for DLST Antibody (4D7)

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug]

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug]

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug] - Detection against Immunogen (36.63 KDa) .
Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug]

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug]

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug] - Analysis of DLST expression in transfected 293T cell line by DLST monoclonal antibody (M01), clone 4D7. Lane 1: DLST transfected lysate (Predicted MW: 48.8 KDa). Lane 2: Non-transfected lysate.
Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug]

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug]

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug] - Analysis of DLST expression in PC-12.
View 1 more images

Applications for DLST Antibody (4D7)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DLST

DLST, also known as Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, is a 48.8 kDa, 453 amino acid protein that is involved in catalyzing the reaction of 2-oxoglutarate into succinyl-CoA and carbon dioxide. Current research is investigating the effect of the protein on malaria, neurodegeneration, pneumonia, cat-scratch disease, ataxia, prostatitis, Parkinson's disease, and Alzheimer's disease. The protein is involved in lysine degradation, citric acid cycle (TCA cycle), and metabolism pathways where it interacts with FLII, ATP6V1B2, HSPD1, UMPS, and DDOST.

Alternate Names

2-oxoglutarate dehydrogenase complex component E2, dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutaratecomplex), Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenasecomplex, dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutaratedehydrogenase complex, mitochondrial, DLTS, E2K, EC 2.3.1, EC 2.3.1.61, OGDC-E2

Entrez Gene IDs

1743 (Human)

Gene Symbol

DLST

OMIM

126063 (Human)

UniProt

NP_001924 (Human)

Additional DLST Products

Product Documents for DLST Antibody (4D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DLST Antibody (4D7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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