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DMAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24791

Novus Biologicals, part of Bio-Techne
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NBP3-24791

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for DMAP1 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein DMAP1 using the following amino acid sequence: AEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DMAP1 Antibody

DMAP1 Antibody Immunohistochemistry-Paraffin: DMAP1 Antibody [NBP3-24791]

Immunohistochemistry-Paraffin: DMAP1 Antibody [NBP3-24791]

Staining of human adrenal gland shows strong nuclear positivity in glandular cells.

Applications for DMAP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DMAP1

DMAP1 (DNA methyltransferase 1 associated protein 1) has been identified as a subunit of several distinct protein complexes involved in the repression and activation of transcription. It has been observed to interact with histone deacetylase 2 (HDAC2) as well as histone acetyltransferase (HAT) indicating a role in nucleosome modification to regulate transcription. DMAP1 can act independently to repress transcription in association with DNA methyltransferase 1. Alternate names for DMAP1 include DNMT1-associated protein 1, DNMAP1, DMAP1, KIAA1425, EAF2, SWC4, DNMAP1, DNMTAP1, FLJ11543, and DKFZp686L09142.

Alternate Names

DNA methyltransferase 1 associated protein 1, DNA methyltransferase 1-associated protein 1, DNMAP1DNMT1-associated protein 1, DNMT1 associated protein 1, DNMTAP1, EAF2, FLJ11543, KIAA1425DKFZp686L09142, MEAF2, SWC4

Gene Symbol

DMAP1

Additional DMAP1 Products

Product Documents for DMAP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DMAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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