DMRT1 Antibody (1G11)

Novus Biologicals, part of Bio-Techne | Catalog # H00001761-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1G11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DMRT1 Antibodies »

Product Specifications

Immunogen

DMRT1 (AAH40847.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEPSSFTVTPVIEEDE

Specificity

DMRT1 - doublesex and mab-3 related transcription factor 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for DMRT1 Antibody (1G11)

Western Blot: DMRT1 Antibody (1G11) [H00001761-M01]

Western Blot: DMRT1 Antibody (1G11) [H00001761-M01]

Western Blot: DMRT1 Antibody (1G11) [H00001761-M01] - Analysis of DMRT1 expression in transfected 293T cell line by DMRT1 monoclonal antibody (M01), clone 1G11.Lane 1: DMRT1 transfected lysate(39.5 KDa).Lane 2: Non-transfected lysate.
Western Blot: DMRT1 Antibody (1G11) [H00001761-M01]

Western Blot: DMRT1 Antibody (1G11) [H00001761-M01]

Western Blot: DMRT1 Antibody (1G11) [H00001761-M01] - DMRT1 monoclonal antibody (M01), clone 1G11 Analysis of DMRT1 expression in HL-60.
Sandwich ELISA: DMRT1 Antibody (1G11) [H00001761-M01] - Detection limit for recombinant GST tagged DMRT1 is approximately 0.3ng/ml as a capture antibody.

Applications for DMRT1 Antibody (1G11)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DMRT1

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Alternate Names

DM domain expressed in testis 1, DMT1DM domain expressed in testis protein 1, doublesex and mab-3 related transcription factor 1, doublesex- and mab-3-related transcription factor 1

Entrez Gene IDs

1761 (Human)

Gene Symbol

DMRT1

OMIM

602424 (Human)

UniProt

AAH40847 (Human)

Additional DMRT1 Products

Product Documents for DMRT1 Antibody (1G11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DMRT1 Antibody (1G11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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