DMTF1 Antibody (5C6)

Novus Biologicals, part of Bio-Techne | Catalog # H00009988-M03

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 5C6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DMTF1 Antibodies »

Product Specifications

Immunogen

DMTF1 (NP_066968, 661 a.a. ~ 760 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KQEESPSDLASAYVTEGLESPTIEEQVDQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH

Reactivity Notes

Human. Other species not tested.

Specificity

DMTF1 - cyclin D binding myb-like transcription factor 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for DMTF1 Antibody (5C6)

Western Blot: DMTF1 Antibody (5C6) [H00009988-M03]

Western Blot: DMTF1 Antibody (5C6) [H00009988-M03]

Western Blot: DMTF1 Antibody (5C6) [H00009988-M03] - Analysis of DMTF1 expression in Hela S3 NE (Cat # L013V3).
Immunocytochemistry/ Immunofluorescence: DMTF1 Antibody (5C6) [H00009988-M03]

Immunocytochemistry/ Immunofluorescence: DMTF1 Antibody (5C6) [H00009988-M03]

Immunocytochemistry/Immunofluorescence: DMTF1 Antibody (5C6) [H00009988-M03] - Analysis of monoclonal antibody to DMTF1 on HeLa cell. Antibody concentration 30 ug/ml
Immunohistochemistry-Paraffin: DMTF1 Antibody (5C6) [H00009988-M03]

Immunohistochemistry-Paraffin: DMTF1 Antibody (5C6) [H00009988-M03]

Immunohistochemistry-Paraffin: DMTF1 Antibody (5C6) [H00009988-M03] - Analysis of monoclonal antibody to DMTF1 on formalin-fixed paraffin-embedded human colon. Antibody concentration 1 ug/ml

Applications for DMTF1 Antibody (5C6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DMTF1

This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

cyclin D binding myb-like transcription factor 1, cyclin D-binding Myb-like protein 1, cyclin-D-binding Myb-like transcription factor 1, Cyclin-D-interacting Myb-like protein 1, DMP1FLJ76054, FLJ25188, FLJ41265, hDMP1DMTF, hDMTF1

Entrez Gene IDs

9988 (Human)

Gene Symbol

DMTF1

OMIM

608491 (Human)

UniProt

NP_066968 (Human)

Additional DMTF1 Products

Product Documents for DMTF1 Antibody (5C6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DMTF1 Antibody (5C6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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