Dnd1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24796

Novus Biologicals, part of Bio-Techne
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NBP3-24796
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Dnd1 Antibodies »

Product Summary for Dnd1 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Dnd1 using the following amino acid sequence: MMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTEKCELSVDGLPPNLTRSALLLALQPLGPGLQE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dnd1 Antibody

Dnd1 Antibody Immunocytochemistry/Immunofluorescence: Dnd1 Antibody [NBP3-24796]

Immunocytochemistry/Immunofluorescence: Dnd1 Antibody [NBP3-24796]

Staining of human cell line HAP1 shows localization to nucleoplasm.

Applications for Dnd1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dnd1

RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression.Relieves miRNA repression in germline cells . Prohibits the function of several miRNAs by blocking theaccessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs)in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordialgerm cell (PGC) survival . However, does not seem to be essential for PGC migration

Alternate Names

dead end homolog 1 (zebrafish), dead end protein homolog 1, RBMS4MGC34750, RNA-binding motif, single-stranded-interacting protein 4

Gene Symbol

DND1

Additional Dnd1 Products

Product Documents for Dnd1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Dnd1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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