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DNER Antibody (4E8)

Novus Biologicals, part of Bio-Techne | Catalog # H00092737-M03

Novus Biologicals, part of Bio-Techne
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H00092737-M03

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 4E8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

DNER (NP_620711, 368 a.a. ~ 476 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP

Specificity

DNER - delta-notch-like EGF repeat-containing transmembrane

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Scientific Data Images for DNER Antibody (4E8)

Western Blot: DNER Antibody (4E8) [H00092737-M03]

Western Blot: DNER Antibody (4E8) [H00092737-M03]

Western Blot: DNER Antibody (4E8) [H00092737-M03] - DNER monoclonal antibody (M03), clone 4E8 Western Blot analysis of DNER expression in PC-12 ( Cat # L012V1 ).

Applications for DNER Antibody (4E8)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DNER

DNER, also known as Delta and Notch-like epidermal growth factor-related receptor, is a 78.5 kDa, 737 amino acid protein and is involved in activating the NOTCH1 pathway. Current research is being conducted on diseases and disorders such as hepatitis, neuronitis and pathological gambling. The protein interacts with other proteins such as NOTCH1, APH1A, ZNF24, AP1G1, and DTX1 in Notch signaling pathways.

Long Name

Delta/Notch-like EGF Repeat-containing Transmembrane

Alternate Names

BET, delta and Notch-like epidermal growth factor-related receptor, delta/notch-like EGF repeat containing, delta-notch-like EGF repeat-containing transmembrane, H_NH0150O02.1, UNQ26, WUGSC:H_NH0150O02.1

Entrez Gene IDs

92737 (Human)

Gene Symbol

DNER

OMIM

607299 (Human)

UniProt

Additional DNER Products

Product Documents for DNER Antibody (4E8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DNER Antibody (4E8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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