Dnmt3L Antibody (2D10H11) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61756

Novus Biologicals, part of Bio-Techne
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NBP2-61756
NBP2-61756-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2D10H11

Format

BSA Free

Concentration

1 mg/ml

View all Dnmt3L Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human DNMT3L (AA: 147-386) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

43.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Dnmt3L Antibody (2D10H11) - BSA Free

Western Blot: Dnmt3L Antibody (2D10H11)BSA Free [NBP2-61756]

Western Blot: Dnmt3L Antibody (2D10H11)BSA Free [NBP2-61756]

Western Blot: Dnmt3L Antibody (2D10H11) [NBP2-61756] - Analysis using DNMT3L mAb against human DNMT3L (AA: 147-386) recombinant protein. (Expected MW is 53.9 kDa)
Flow Cytometry: Dnmt3L Antibody (2D10H11) - BSA Free [NBP2-61756]

Flow Cytometry: Dnmt3L Antibody (2D10H11) - BSA Free [NBP2-61756]

Flow Cytometry: Dnmt3L Antibody (2D10H11) [NBP2-61756] - Analysis of HepG2 cells using DNMT3L mouse mAb (green) and negative control (red).
Western Blot: Dnmt3L Antibody (2D10H11)BSA Free [NBP2-61756]

Western Blot: Dnmt3L Antibody (2D10H11)BSA Free [NBP2-61756]

Western Blot: Dnmt3L Antibody (2D10H11) [NBP2-61756] - Analysis using DNMT3L mAb against HEK293 (1) and DNMT3L (AA: 147-386)-hIgGFc transfected HEK293 (2) cell lysate.
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Applications for Dnmt3L Antibody (2D10H11) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dnmt3L

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.;

Alternate Names

DNA (cytosine-5-)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3-like, human cytosine-5-methyltransferase 3-like protein, 10cytosine-5-methyltransferase 3-like protein, MGC1090

Gene Symbol

DNMT3L

Additional Dnmt3L Products

Product Documents for Dnmt3L Antibody (2D10H11) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Dnmt3L Antibody (2D10H11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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