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DOK7 Antibody (OTI1A9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-02073

Novus Biologicals, part of Bio-Techne
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NBP2-02073
Conjugate
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1A9

Concentration

1 mg/ml

Product Specifications

Immunogen

Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

52.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DOK7 Antibody (OTI1A9)

Western Blot: DOK7 Antibody (1A9) [NBP2-02073] Analysis of extracts (35ug) from 9 different cell lines by usin g anti-DOK7 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunocytochemistry/ Immunofluorescence: DOK7 Antibody (OTI1A9) [NBP2-02073]

Immunocytochemistry/ Immunofluorescence: DOK7 Antibody (OTI1A9) [NBP2-02073]

Immunocytochemistry/Immunofluorescence: DOK7 Antibody (1A9) [NBP2-02073] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY DOK7.
Immunohistochemistry-Paraffin: DOK7 Antibody (OTI1A9) [NBP2-02073]

Immunohistochemistry-Paraffin: DOK7 Antibody (OTI1A9) [NBP2-02073]

Immunohistochemistry-Paraffin: DOK7 Antibody (1A9) [NBP2-02073] - Staining of paraffin-embedded Human prostate tissue using anti-DOK7 mouse monoclonal antibody.

Applications for DOK7 Antibody (OTI1A9)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:500-2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DOK7

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Long Name

Downstream of Tyrosine Kinase 7

Alternate Names

C4orf25, CMS1B

Entrez Gene IDs

285489 (Human)

Gene Symbol

DOK7

Additional DOK7 Products

Product Documents for DOK7 Antibody (OTI1A9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DOK7 Antibody (OTI1A9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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