DOK7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32465

Novus Biologicals, part of Bio-Techne
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NBP2-32465
NBP2-32465-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DOK7 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DOK7 Antibody

Western Blot: DOK7 Antibody [NBP2-32465]

Western Blot: DOK7 Antibody [NBP2-32465]

Western Blot: DOK7 Antibody [NBP2-32465] - Analysis in human cell line MCF-7 and human cell line SK-MEL-30.
Immunocytochemistry/ Immunofluorescence: DOK7 Antibody [NBP2-32465]

Immunocytochemistry/ Immunofluorescence: DOK7 Antibody [NBP2-32465]

Immunocytochemistry/Immunofluorescence: DOK7 Antibody [NBP2-32465] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: DOK7 Antibody [NBP2-32465]

Immunohistochemistry-Paraffin: DOK7 Antibody [NBP2-32465]

Immunohistochemistry-Paraffin: DOK7 Antibody [NBP2-32465] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.
View 1 more images

Applications for DOK7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DOK7

DOK7 (Downstream of kinase 7) is a 55 kDa member of the DOK family of cytoplasmic adaptor proteins. It links the acetylcholine receptor and the receptor tyrosine kinase MuSK in skeletal and cardiac muscle. Mutations can cause familial myasthenic syndromes. DOK7 contains pleckstrin homology, phosphotyrosine-binding and SH2 domains, and a C-terminal nuclear export signal. Multiple isoforms exist.

Long Name

Downstream of Tyrosine Kinase 7

Alternate Names

C4orf25, CMS1B

Gene Symbol

DOK7

Additional DOK7 Products

Product Documents for DOK7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DOK7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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