Dopamine D1R/DRD1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS44

Novus Biologicals, part of Bio-Techne
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NLS44
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all Dopamine D1R/DRD1 Antibodies »

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from C-terminus of human Dopamine D1R/DRD1.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Gibbon (94%), Rat (88%), Porcine (88%), Sheep (82%), Hamster (82%), Bovine (82%).

Localization

Cell membrane; multi pass membrane protein.

Specificity

Human DRD1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Dopamine D1R/DRD1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44]

Immunohistochemistry-Paraffin: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44]

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - Anti-DRD1 / Dopamine Receptor D1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44]

Immunohistochemistry-Paraffin: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44]

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - Human Kidney: Formalin-Fixed Paraffin-Embedded (FFPE)
Immunohistochemistry-Paraffin: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44]

Immunohistochemistry-Paraffin: Dopamine D1R/DRD1 Antibody - BSA Free [NLS44]

Immunohistochemistry-Paraffin: Dopamine D1 R/DRD1 Antibody [NLS44] - IHC staining of human kidney, tubules.
View 3 more images

Applications for Dopamine D1R/DRD1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5-10 ug/ml
Application Notes
ICC: Does not work..
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Dopamine D1R/DRD1

DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension. Dopamine receptor D1 has been reported mostly in various regions of the brain. ESTs have been isolated from normal olfactory epithelium and cancerous genitourinary tract libraries.

Long Name

Dopamine D1 Receptor

Alternate Names

DADR, Dopamine D1 R, DRD1

Entrez Gene IDs

1812 (Human)

Gene Symbol

DRD1

UniProt

P21728

Additional Dopamine D1R/DRD1 Products

Product Documents for Dopamine D1R/DRD1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dopamine D1R/DRD1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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