Dopamine D3R/DRD3 Antibody (5B10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15187

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15187
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 5B10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Dopamine D3 R/DRD3 Antibodies »

Product Summary for Dopamine D3R/DRD3 Antibody (5B10)

Immunogen

A synthesized peptide derived from human Dopamine D3R/DRD3. UniProt ID (P35462).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dopamine D3R/DRD3 Antibody (5B10)

Western Blot: Dopamine D3R/DRD3 Antibody (5B10) [NBP3-15187]

Western Blot: Dopamine D3R/DRD3 Antibody (5B10) [NBP3-15187]

Western Blot: Dopamine D3R/DRD3 Antibody (5B10) [NBP3-15187] - Positive WB detected in: Hela whole cell lysate, U-251 whole cell lysate, U-87 whole cell lysate, K562 whole cell lysate, HL-60 whole cell lysate, Rat Spleen whole cell lysate, Rat Brain whole cell lysate. All lanes: Dopamine D3R/DRD3 antibody at 1:1000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45, 41 KDa. Observed band size: 50 KDa.

Applications for Dopamine D3R/DRD3 Antibody (5B10)

Application
Recommended Usage

Western Blot

1:500-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Dopamine D3 R/DRD3

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Long Name

Dopamine D3 Receptor

Alternate Names

D3DR, Dopamine D3R, DRD3, ETM1, FET1

Gene Symbol

DRD3

Additional Dopamine D3 R/DRD3 Products

Product Documents for Dopamine D3R/DRD3 Antibody (5B10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Dopamine D3R/DRD3 Antibody (5B10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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