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Dopamine D3R/DRD3 Antibody (SR1747)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21963

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-21963-100ul
NBP3-21963-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1747

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Dopamine D3R/DRD3 Antibody (SR1747)

Immunogen

A synthesized peptide derived from human Dopamine D3R/DRD3 (Uniprot #: P35462)

Specificity

Detects endogenous levels of total Dopamine D3R/DRD3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Dopamine D3R/DRD3 Antibody (SR1747)

Western Blot: Dopamine D3R/DRD3 Antibody (SR1747) [NBP3-21963] -

Western Blot: Dopamine D3R/DRD3 Antibody (SR1747) [NBP3-21963] - Western blot analysis using NBP3-21963 in SH-SY5Y cell lysate.

Applications for Dopamine D3R/DRD3 Antibody (SR1747)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dopamine D3 R/DRD3

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Long Name

Dopamine D3 Receptor

Alternate Names

D3DR, Dopamine D3R, DRD3, ETM1, FET1

Gene Symbol

DRD3

Additional Dopamine D3 R/DRD3 Products

Product Documents for Dopamine D3R/DRD3 Antibody (SR1747)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dopamine D3R/DRD3 Antibody (SR1747)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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