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Dopamine D3R/DRD3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-84009

Novus Biologicals, part of Bio-Techne
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NBP2-84009-0.1ml

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for Dopamine D3R/DRD3 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal Dopamine D3R/DRD3. Peptide sequence: QERGGELKREEKTRNSLMPLREKKATQMVAIVLGAFIVCWLPFFLTHVLN The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Dopamine D3R/DRD3 Antibody

Western Blot: Dopamine D3R/DRD3 Antibody [NBP2-84009]

Western Blot: Dopamine D3R/DRD3 Antibody [NBP2-84009]

Western Blot: Dopamine D3R/DRD3 Antibody [NBP2-84009] - WB Suggested Anti-DRD3 Antibody. Titration: 1.0 ug/ml. Positive Control: HepG2 Whole Cell

Applications for Dopamine D3R/DRD3 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dopamine D3 R/DRD3

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Long Name

Dopamine D3 Receptor

Alternate Names

D3DR, Dopamine D3R, DRD3, ETM1, FET1

Gene Symbol

DRD3

Additional Dopamine D3 R/DRD3 Products

Product Documents for Dopamine D3R/DRD3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dopamine D3R/DRD3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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