DP1 Antibody (SR1878)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22278

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22278-100ul
NBP3-22278-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1878

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DP1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human DP1 (Uniprot #: Q14186)

Specificity

Detects endogenous levels of total DP1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DP1 Antibody (SR1878)

Western Blot: DP1 Antibody (SR1878) [NBP3-22278] -

Western Blot: DP1 Antibody (SR1878) [NBP3-22278] - Western blot analysis using NBP3-22278 in Raji cell lysate.

Applications for DP1 Antibody (SR1878)

Application
Recommended Usage

Flow Cytometry

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DP1

The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 forms heterodimers with a second protein, designated DP-1, forming an

Alternate Names

DP1E2F dimerization partner 1, DRTF1Dp-1, DRTF1-polypeptide 1, E2F-related transcription factor, transcription factor Dp-1

Gene Symbol

TFDP1

Additional DP1 Products

Product Documents for DP1 Antibody (SR1878)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DP1 Antibody (SR1878)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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