DPM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16220

Novus Biologicals, part of Bio-Techne
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NBP2-16220
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (91%), Porcine (92%), Rat (90%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DPM1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human DPM1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Xenopus laevis (85%), Mouse (89%).

Localization

Endoplasmic reticulum

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DPM1 Antibody

Western Blot: DPM1 Antibody [NBP2-16220]

Western Blot: DPM1 Antibody [NBP2-16220]

Western Blot: DPM1 Antibody [NBP2-16220] - Sample (30 ug of whole cell lysate) A: U87-MG 12% SDS PAGE gel, diluted at 1:1000.

Applications for DPM1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: DPM1

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq]

Alternate Names

CDGIEEC 2.4.1.83, dolichol monophosphate mannose synthase, dolichol-phosphate mannosyltransferase, Dolichyl-phosphate beta-D-mannosyltransferase, dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit, DPM synthase, Mannose-P-dolichol synthase, MPD synthase, MPDSDolichol-phosphate mannose synthase

Gene Symbol

DPM1

UniProt

O60762 (Human)

Additional DPM1 Products

Product Documents for DPM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DPM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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