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DPYD Antibody (C1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41699

Novus Biologicals, part of Bio-Techne
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NBP3-41699

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C1

Concentration

1 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Human DPYD (Uniprot#: Q12882; Ile781-Cys1025 (Uniprot#: Q12882)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for DPYD Antibody (C1)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.2-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DPYD

DPYD is encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

Alternate Names

DHP, DHPDHASE, dihydropyrimidine dehydrogenase, dihydropyrimidine dehydrogenase [NADP+], Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPDMGC132008, EC 1.3.1.2, MGC70799

Gene Symbol

DPYD

Additional DPYD Products

Product Documents for DPYD Antibody (C1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DPYD Antibody (C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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