DR6/TNFRSF21 Antibody (Abbvie patent anti-TNFRSF21) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28486JF646

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-28486

Alexa Fluor 350

NBP3-28486AF350

Alexa Fluor 405

NBP3-28486AF405

Alexa Fluor 488

NBP3-28486AF488

Alexa Fluor 532

NBP3-28486AF532

Alexa Fluor 594

NBP3-28486AF594

Alexa Fluor 647

NBP3-28486AF647

Alexa Fluor 700

NBP3-28486AF700

Alexa Fluor 750

NBP3-28486AF750

Allophycocyanin

NBP3-28486APC

Biotin

NBP3-28486B

CoraFluor 1

NBP3-28486CL1

DyLight 350

NBP3-28486UV

DyLight 405

NBP3-28486V

DyLight 488

NBP3-28486G

DyLight 550

NBP3-28486R

DyLight 594

NBP3-28486DL594

DyLight 650

NBP3-28486C

DyLight 680

NBP3-28486FR

DyLight 755

NBP3-28486IR

FITC

NBP3-28486F

HRP

NBP3-28486H

Janelia Fluor 525

NBP3-28486JF525

Janelia Fluor 549

NBP3-28486JF549

Janelia Fluor 585

NBP3-28486JF585

Janelia Fluor 635

NBP3-28486JF635

Janelia Fluor 669

NBP3-28486JF669

mFluor Violet 450 SE

NBP3-28486MFV450

mFluor Violet 500 SE

NBP3-28486MFV500

mFluor Violet 610 SE

NBP3-28486MFV610

PE

NBP3-28486PE

PerCP

NBP3-28486PCP

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Janelia Fluor 646

Antibody Source

Recombinant Monoclonal Human IgG₁ Clone # Abbvie patent anti-TNFRSF21

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DR6/TNFRSF21 Antibodies »

Product Summary

Immunogen

TNFRSF21 / DR6 / CD358

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Applications

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: DR6/TNFRSF21

Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNFR1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed inhuman tissues and cell lines. The ligand for DR6 hasnot been identified.

Long Name

Death Receptor 6

Alternate Names

BM-018, CD358, TNFRSF21

Gene Symbol

TNFRSF21

Additional DR6/TNFRSF21 Products

Product Documents

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Reviews

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